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BDBM50353332 CHEMBL1830694

SMILES: Cc1sc(Nc2ccccn2)nc1-c1cn[nH]c1

InChI Key: InChIKey=GNTYTRMYRRTNNR-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353332   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50353332
PNG
(CHEMBL1830694)
Show SMILES Cc1sc(Nc2ccccn2)nc1-c1cn[nH]c1
Show InChI InChI=1S/C12H11N5S/c1-8-11(9-6-14-15-7-9)17-12(18-8)16-10-4-2-3-5-13-10/h2-7H,1H3,(H,14,15)(H,13,16,17)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...


J Med Chem 54: 5070-81 (2011)

More data for this
Ligand-Target Pair