BDBM50353855 CHEMBL1831166::US9604926, Compound CM-361::US9724435, Compound CM-361
SMILES COc1cc2CCN(CCCCn3cc(-c4ccc(F)cc4)c4ccccc34)Cc2cc1OC
InChI Key InChIKey=SAUWBVJOXSKPQX-UHFFFAOYSA-N
Data 13 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50353855
Affinity DataKi: 4.37nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Affinity DataKi: 4.37nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
The University Of Mississippi
Curated by ChEMBL
The University Of Mississippi
Curated by ChEMBL
Affinity DataKi: 295nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 544nMAssay Description:Displacement of [3H]YM-09151-2 from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 870nMAssay Description:Displacement of [3H]YM-09151-2 from human D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The University Of Mississippi
Curated by ChEMBL
The University Of Mississippi
Curated by ChEMBL
Affinity DataKi: 1.27E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The University Of Mississippi
Curated by ChEMBL
The University Of Mississippi
Curated by ChEMBL
Affinity DataKi: 1.35E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The University Of Mississippi
Curated by ChEMBL
The University Of Mississippi
Curated by ChEMBL
Affinity DataKi: 1.51E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.95E+3nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat brain membrane after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.71E+3nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi
US Patent
The University Of Mississippi
US Patent
Affinity DataKi: 4.71E+3nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Mississippi
Curated by ChEMBL
The University Of Mississippi
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from human D1 receptor in cell-based assayMore data for this Ligand-Target Pair