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BDBM50353957 CHEMBL1831190

SMILES: CCc1cc([C@@H]2CC(=O)N2c2ccc(OC)cc2)c(O)cc1O

InChI Key: InChIKey=XFUKTUJTJFMDKB-HNNXBMFYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353957   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM50353957
PNG
(CHEMBL1831190)
Show SMILES CCc1cc([C@@H]2CC(=O)N2c2ccc(OC)cc2)c(O)cc1O
Show InChI InChI=1S/C18H19NO4/c1-3-11-8-14(17(21)10-16(11)20)15-9-18(22)19(15)12-4-6-13(23-2)7-5-12/h4-8,10,15,20-21H,3,9H2,1-2H3/t15-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Displacement of FITC-labeled geldanamycin from human recombinant HSP90alpha after 24 hrs by fluorescence diplacement assay


Bioorg Med Chem 19: 6055-68 (2011)


Article DOI: 10.1016/j.bmc.2011.08.048
BindingDB Entry DOI: 10.7270/Q2J38SZQ
More data for this
Ligand-Target Pair