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BDBM50354080 CHEMBL1836328

SMILES: COc1ccc2-c3nc(NC[C@H]4CC[C@@H](CC4)NS(C)(=O)=O)sc3CCOc2c1

InChI Key: InChIKey=BWTFCVIDGIPNSZ-HDJSIYSDSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354080   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50354080
PNG
(CHEMBL1836328)
Show SMILES COc1ccc2-c3nc(NC[C@H]4CC[C@@H](CC4)NS(C)(=O)=O)sc3CCOc2c1
Show InChI InChI=1S/C20H27N3O4S2/c1-26-15-7-8-16-17(11-15)27-10-9-18-19(16)22-20(28-18)21-12-13-3-5-14(6-4-13)23-29(2,24)25/h7-8,11,13-14,23H,3-6,9-10,12H2,1-2H3,(H,21,22)/t13-,14-
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Similars

Article
PubMed
6.70n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 21: 5436-41 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K
More data for this
Ligand-Target Pair