BDBM50354191 CHEMBL1836147

SMILES: COc1cccc(CN2CCC(CNC(=O)c3cc(OC)cc(OC)c3)(CC2)C#N)c1

InChI Key: InChIKey=RDARPBAZEBQWOY-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50354191 (CHEMBL1836147) Show SMILES COc1cccc(CN2CCC(CNC(=O)c3cc(OC)cc(OC)c3)(CC2)C#N)c1 Show InChI InChI=1S/C24H29N3O4/c1-29-20-6-4-5-18(11-20)15-27-9-7-24(16-25,8-10-27)17-26-23(28)19-12-21(30-2)14-22(13-19)31-3/h4-6,11-14H,7-10,15,17H2,1-3H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 21: 5910-5 (2011) Article DOI: 10.1016/j.bmcl.2011.07.087 BindingDB Entry DOI: 10.7270/Q2VD6ZT4
					More data for this Ligand-Target Pair