BDBM50354486 CHEMBL411043
SMILES ClC(Cn1ncc2c(NCc3ccccc3)ncnc12)c1ccccc1
InChI Key InChIKey=SEFWYTXTKMMUEF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50354486
Affinity DataKi: 370nMAssay Description:Inhibition of human wild type full length N-terminal GST/6His-tagged ABL (P118 to S535 residues) expressed in Sf9 cells using abltide as substrate af...More data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Inhibition human recombinant Abl using Abtide peptide substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
Affinity DataKi: 372nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena
Curated by ChEMBL
University Of Siena
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition human recombinant cSRC using KVEKIGEGTYGVVYK peptide substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena
Curated by ChEMBL
University Of Siena
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of human wild type full length N-terminal GST/6His-tagged SRC (M1 to L536 residues) expressed in baculovirus infected Sf9 cells using src ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena
Curated by ChEMBL
University Of Siena
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena
Curated by ChEMBL
University Of Siena
Curated by ChEMBL
Affinity DataKi: 3.02E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena
Curated by ChEMBL
University Of Siena
Curated by ChEMBL
Affinity DataKi: 3.16E+3nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataKi: 3.47E+3nMAssay Description:Inhibition of FYN (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataKi: 3.47E+3nMAssay Description:Inhibition of FGR (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataKi: 3.47E+3nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataKi: 3.47E+3nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR2 expressed in porcine aortic endothelial cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair