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BDBM50354690 CHEMBL1834043

SMILES: Cc1ccc(CNC(=O)c2c(N)n(-c3cccc(O)c3)c3nc4ccccc4nc23)cc1

InChI Key: InChIKey=ZEFANEBOMGSMNZ-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354690   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50354690
PNG
(CHEMBL1834043)
Show SMILES Cc1ccc(CNC(=O)c2c(N)n(-c3cccc(O)c3)c3nc4ccccc4nc23)cc1
Show InChI InChI=1S/C25H21N5O2/c1-15-9-11-16(12-10-15)14-27-25(32)21-22-24(29-20-8-3-2-7-19(20)28-22)30(23(21)26)17-5-4-6-18(31)13-17/h2-13,31H,14,26H2,1H3,(H,27,32)
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MMDB

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PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.26E+4n/an/an/an/an/a



Sejong University

Curated by ChEMBL


Assay Description
Inhibition of BRAF


Bioorg Med Chem Lett 21: 5753-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.010
BindingDB Entry DOI: 10.7270/Q2RJ4JWR
More data for this
Ligand-Target Pair