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BDBM50354752 CHEMBL1834113

SMILES: Nc1c(F)c(NCCc2ccccc2)c(F)c2n(cc(C(O)=O)c(=O)c12)C1CC1

InChI Key: InChIKey=ZOKYLRYNFLLZQF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354752   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Axin-1/Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50354752
PNG
(CHEMBL1834113)
Show SMILES Nc1c(F)c(NCCc2ccccc2)c(F)c2n(cc(C(O)=O)c(=O)c12)C1CC1
Show InChI InChI=1S/C21H19F2N3O3/c22-15-17(24)14-19(26(12-6-7-12)10-13(20(14)27)21(28)29)16(23)18(15)25-9-8-11-4-2-1-3-5-11/h1-5,10,12,25H,6-9,24H2,(H,28,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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antibodypedia
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CHEMBL
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PC sid
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Patents


Similars

Article
PubMed
n/an/a 440n/an/an/an/an/an/a



ActivX Biosciences Inc

Curated by ChEMBL


Assay Description
Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assay


Bioorg Med Chem Lett 21: 5948-51 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.073
BindingDB Entry DOI: 10.7270/Q23T9HMH
More data for this
Ligand-Target Pair