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BDBM50354946 CHEMBL1836879

SMILES: COCCCN1CCN(CC1)c1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)cn1

InChI Key: InChIKey=GSXZJZKGQYJCCD-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50354946   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))
BDBM50354946
PNG
(CHEMBL1836879)
Show SMILES COCCCN1CCN(CC1)c1ccc(Cn2c3cc(nc(N)c3[nH]c2=O)C(F)(F)F)cn1
Show InChI InChI=1S/C21H26F3N7O2/c1-33-10-2-5-29-6-8-30(9-7-29)17-4-3-14(12-26-17)13-31-15-11-16(21(22,23)24)27-19(25)18(15)28-20(31)32/h3-4,11-12H,2,5-10,13H2,1H3,(H2,25,27)(H,28,32)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.70n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Agonist activity at TLR7 in human PBMC assessed as induction of type 1 interferon production


Bioorg Med Chem Lett 21: 5939-43 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.076
BindingDB Entry DOI: 10.7270/Q2PK0GJN
More data for this
Ligand-Target Pair