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BDBM50355010 CHEMBL1834961

SMILES: OC(=O)c1cc(ccc1O)N=Nc1ccccc1

InChI Key: InChIKey=JHDYSXXPQIFFJZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355010   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cystine/glutamate transporter


(Homo sapiens (Human))
BDBM50355010
PNG
(CHEMBL1834961)
Show SMILES OC(=O)c1cc(ccc1O)N=Nc1ccccc1
Show InChI InChI=1S/C13H10N2O3/c16-12-7-6-10(8-11(12)13(17)18)15-14-9-4-2-1-3-5-9/h1-8,16H,(H,17,18)
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Similars

Article
PubMed
n/an/a 2.00E+5n/an/an/an/an/an/a



Johns Hopkins University

Curated by ChEMBL


Assay Description
Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...


Bioorg Med Chem Lett 21: 6184-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.081
BindingDB Entry DOI: 10.7270/Q21V5FCR
More data for this
Ligand-Target Pair