BDBM50355027 CHEMBL1835056

SMILES: CC(=O)Oc1cccc(c1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key: InChIKey=NUPUXBPWNYDLDR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep))	BDBM50355027 (CHEMBL1835056) Show SMILES CC(=O)Oc1cccc(c1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H14F3N3O4S/c1-11(25)28-14-4-2-3-12(9-14)16-10-17(18(19,20)21)23-24(16)13-5-7-15(8-6-13)29(22,26)27/h2-10H,1H3,(H2,22,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX2 by enzyme immuno assay				Bioorg Med Chem Lett 21: 6074-80 (2011) Article DOI: 10.1016/j.bmcl.2011.08.053 BindingDB Entry DOI: 10.7270/Q2NK3FD8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50355027 (CHEMBL1835056) Show SMILES CC(=O)Oc1cccc(c1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H14F3N3O4S/c1-11(25)28-14-4-2-3-12(9-14)16-10-17(18(19,20)21)23-24(16)13-5-7-15(8-6-13)29(22,26)27/h2-10H,1H3,(H2,22,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by enzyme immuno assay				Bioorg Med Chem Lett 21: 6074-80 (2011) Article DOI: 10.1016/j.bmcl.2011.08.053 BindingDB Entry DOI: 10.7270/Q2NK3FD8
					More data for this Ligand-Target Pair