BDBM50355207 CHEMBL1835521

SMILES Cc1cccc(n1)-c1nn(cc1-c1ccc2ncnn2c1)C(=S)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=HNSNXHZPUIPOMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355207   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50355207(CHEMBL1835521)
Affinity DataIC50:  3.01nMAssay Description:Inhibition of human recombinant GST-fused ALK5 expressed in Sf9 cells using casein as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50355207(CHEMBL1835521)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as a substrate by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed