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BDBM50355331 CHEMBL1835342

SMILES: ONC(=O)CCCCCNC(=O)[C@@H]1CC2(CN1)SCCS2

InChI Key: InChIKey=FBXHXMCJSSFWCT-UEQNJFAPNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355331   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 8


(Homo sapiens (Human))
BDBM50355331
PNG
(CHEMBL1835342)
Show SMILES ONC(=O)CCCCCNC(=O)[C@@H]1CC2(CN1)SCCS2
Show InChI InChI=1/C13H23N3O3S2/c17-11(16-19)4-2-1-3-5-14-12(18)10-8-13(9-15-10)20-6-7-21-13/h10,15,19H,1-9H2,(H,14,18)(H,16,17)/t10-/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.59E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of human HDAC8 expressed in Escherichia coli using Boc-Lys (acetyl)-AMC as substrate treated for 5 mins before substrate addition measured...


Eur J Med Chem 46: 5387-97 (2011)


Article DOI: 10.1016/j.ejmech.2011.08.045
BindingDB Entry DOI: 10.7270/Q2KP82JT
More data for this
Ligand-Target Pair