BDBM50355499 CHEMBL1908395::CHEMBL1908842

SMILES: CN(C)CC(=O)N1CCC(CC1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1

InChI Key: InChIKey=GUBJNPWVIUFSTR-UHFFFAOYSA-N

Data: 18 IC50  442 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 461 hits for monomerid = 50355499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TNNI3K (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase BRSK1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit alpha (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase MRCK gamma (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-6 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-4 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myotonin-protein kinase (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C eta type (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-A receptor 6 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Insulin receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase kinase 2 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 4 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
SRSF protein kinase 2 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50355499 (CHEMBL1908395 | CHEMBL1908842 | US20250129067, Com...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.830	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair