BDBM50356646 CHEMBL1917389
SMILES OC(=O)COc1ccc(Cl)cc1C#Cc1cccc(Cl)c1
InChI Key InChIKey=LROYLZZPNSRGAA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50356646
Affinity DataKi: 29nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus infected insect cells preincubated for 15 mins measured after 30 mins by luminescence...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Antagonist activity at CRTH2 in human blood cells assessed as inhibition of PGD2-induced eosinophil cell shape change after 10 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting in the presence of 0.1% BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human CRTH2 expressed in human CHO cells by cellular dielectric spectroscopy in the presence of PGD2 and 0.1% BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Antagonist activity at human CRTH2 expressed in human CHO cells by cellular dielectric spectroscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Antagonist activity human CRTH2 expressed in chinese hamster CHO cells assessed as inhibition of PGD2-induced [35S]GTPgamma binding by liquid scintil...More data for this Ligand-Target Pair