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BDBM50356874 CHEMBL1914542

SMILES: Nc1nc(N2CCNCC2)c2oc3ccc(Cl)cc3c2n1

InChI Key: InChIKey=NDLXJQFLHYWQSI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50356874   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H4)


(Homo sapiens (human))
BDBM50356874
PNG
(CHEMBL1914542)
Show SMILES Nc1nc(N2CCNCC2)c2oc3ccc(Cl)cc3c2n1
Show InChI InChI=1S/C14H14ClN5O/c15-8-1-2-10-9(7-8)11-12(21-10)13(19-14(16)18-11)20-5-3-17-4-6-20/h1-2,7,17H,3-6H2,(H2,16,18,19)
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PC sid
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Similars

Article
PubMed
1.10n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from recombinant human histamine H4 receptor


Bioorg Med Chem Lett 21: 6577-81 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.014
BindingDB Entry DOI: 10.7270/Q2CN749X
More data for this
Ligand-Target Pair