BDBM50357205 CHEMBL1914844::CHEMBL1963594

SMILES Cc1ccc(cc1)N1CCN(CC(O)COc2ccccc2C(=O)CCc2ccccc2)CC1

InChI Key InChIKey=ZJYHULVNOMALBG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50357205   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50:  4.31E+3nMAssay Description:Inhibition of human cloned ERG channel expressed in chinese hamster CHO cells after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as tonic inhibition after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human cloned Nav1.5 channel expressed in chinese hamster CHO cells assessed as phasic inhibition after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Kir6.2 by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50:  4.31E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Nav1.5 assessed as tonic inhibition by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Nav1.5 assessed as phasic inhibition by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 9/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50357205(CHEMBL1914844 | CHEMBL1963594)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human kir6.2/SUR2A ion channel coexpressed in human HEK293 cells after 5 mins by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed