BDBM50357620 CHEMBL1915865

SMILES CN1C[C@@H](COc2cc(C)c(C(=O)Nc3cc(ccc3Cl)C3(CC3)C(O)=O)c(C)c2)Oc2ccccc12

InChI Key InChIKey=GUWAOSSGBYSTNR-NRFANRHFSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50357620   

TargetProstacyclin receptor(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357620(CHEMBL1915865)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357620(CHEMBL1915865)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357620(CHEMBL1915865)
Affinity DataIC50:  6.5nMAssay Description:Antagonist activity at prostanoid DP receptor in human platelet rich plasma assessed as inhibition of PGD2-induced intracellular cAMP production afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed