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BDBM50357769 CHEMBL1916406

SMILES: CCOC(=O)CCn1ncc2cc(ccc12)-c1noc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=HRWJVFMINRHRBP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357769   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50357769
PNG
(CHEMBL1916406)
Show SMILES CCOC(=O)CCn1ncc2cc(ccc12)-c1noc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C22H16F6N4O3/c1-2-34-18(33)5-6-32-17-4-3-12(7-14(17)11-29-32)19-30-20(35-31-19)13-8-15(21(23,24)25)10-16(9-13)22(26,27)28/h3-4,7-11H,2,5-6H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a>100n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF a...


Bioorg Med Chem Lett 21: 6013-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.05.110
BindingDB Entry DOI: 10.7270/Q24T6JSB
More data for this
Ligand-Target Pair