BDBM50358213 CHEMBL1922219::US8846696, (2R3S)-3-{9-Isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-pentan-2-ol

SMILES: CC[C@@H]([C@@H](C)O)Nc1nc(c2c(n1)n(cn2)C(C)C)NCc3cccnc3

InChI Key: InChIKey=SCACHXWSWJBIHG-UHFFFAOYSA-N

Data: 19 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50358213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-H/Cyclin-dependent kinase 7 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 6 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	7.4	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.4	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50358213 (CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair