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BDBM50358276 CHEMBL1922342

SMILES: CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1NC(=O)c1ccc(Cl)s1

InChI Key: InChIKey=XXKHAVBPASXEKV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358276   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50358276
PNG
(CHEMBL1922342)
Show SMILES CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1NC(=O)c1ccc(Cl)s1
Show InChI InChI=1S/C24H25ClN4O3S/c1-28-12-3-13-29(15-14-28)17-8-6-16(7-9-17)23(31)27-22-18(4-2-5-19(22)30)26-24(32)20-10-11-21(25)33-20/h2,4-11,30H,3,12-15H2,1H3,(H,26,32)(H,27,31)
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Article
PubMed
n/an/a 41.3n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis


J Med Chem 54: 8051-65 (2011)


Article DOI: 10.1021/jm200868m
BindingDB Entry DOI: 10.7270/Q2D50ND9
More data for this
Ligand-Target Pair