BDBM50358374 CHEMBL1922840

SMILES CCCOc1cc(cc2n(Cc3ccc(cc3)C(=O)Nc3nnn[nH]3)c(=Nc3ccc(cc3)C(F)(F)F)n(C)c12)C(F)(F)F

InChI Key InChIKey=UDEHONWVRSTECM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50358374   

TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358374(CHEMBL1922840)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human GLP1 receptor by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358374(CHEMBL1922840)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human GIP receptor by cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358374(CHEMBL1922840)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced [125I]cAMP accumulation after 30 mins by scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358374(CHEMBL1922840)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed