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BDBM50358731 CHEMBL1922258

SMILES: CC1C2CN(C)CCC2Cc2[nH]c3cc(Cl)c(Cl)cc3c12

InChI Key: InChIKey=UEAKXCHESFVOJA-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358731   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50358731
PNG
(CHEMBL1922258)
Show SMILES CC1C2CN(C)CCC2Cc2[nH]c3cc(Cl)c(Cl)cc3c12
Show InChI InChI=1/C17H20Cl2N2/c1-9-12-8-21(2)4-3-10(12)5-16-17(9)11-6-13(18)14(19)7-15(11)20-16/h6-7,9-10,12,20H,3-5,8H2,1-2H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR1 expressed in Jurkat cells co-expressing apoaequorin assessed as inhibition of MCH-induced calcium mobilization by ...


Bioorg Med Chem Lett 21: 7001-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.110
BindingDB Entry DOI: 10.7270/Q29887FX
More data for this
Ligand-Target Pair