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BDBM50358793 CHEMBL1922782

SMILES: Nc1ncc(cn1)-c1cncc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)c1

InChI Key: InChIKey=ZGSHDYCRILIDKN-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358793   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform


(Homo sapiens (Human))
BDBM50358793
PNG
(CHEMBL1922782)
Show SMILES Nc1ncc(cn1)-c1cncc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)c1
Show InChI InChI=1S/C16H12F3N5O2S/c17-16(18,19)12-2-1-3-14(5-12)27(25,26)24-13-4-10(6-21-9-13)11-7-22-15(20)23-8-11/h1-9,24H,(H2,20,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 430n/an/an/an/an/a



Institute of Science and Technology (KAIST)

Curated by ChEMBL


Assay Description
Binding affinity to PI3Kbeta


Bioorg Med Chem Lett 21: 6977-81 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.118
BindingDB Entry DOI: 10.7270/Q2NK3FFQ
More data for this
Ligand-Target Pair