BDBM50358916 CHEMBL1923569

SMILES C[C@H](O)CN1CCN(CC1)c1ccc(Nc2ncc3ccc(-c4ccccc4N(C)S(C)(=O)=O)n3n2)cc1

InChI Key InChIKey=PUVCWOYYOGTJQF-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358916   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358916(CHEMBL1923569)
Affinity DataIC50:  30nMAssay Description:Inhibition of human GST-tagged ALK expressed in SF21 insect cells using PLCgamma/GST as substrate after 15 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358916(CHEMBL1923569)
Affinity DataIC50:  1.14nMAssay Description:Inhibition of human recombinant JAK2 using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed