BDBM50359256 CHEMBL1923502::ULIMORELIN

SMILES C[C@@H]1CN[C@@H](C2CC2)C(=O)N(C)[C@H](C)C(=O)N[C@H](Cc2ccc(F)cc2)C(=O)NCCCc2ccccc2O1

InChI Key InChIKey=WGYPAJVJMXQXTR-ABNZCKJZSA-N

Data  1 KI  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50359256   

TargetAppetite-regulating hormone(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataKi:  16nMAssay Description:Displacement of [125I-His9]-ghrelin from human GRLN receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universite£

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataEC50:  27nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAppetite-regulating hormone(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human GRLN receptor expressed in HEK293 cells assessed as calcium binding by Ca2+ bioluminescence aequorin assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359256(CHEMBL1923502 | ULIMORELIN)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed