BDBM50359505 CHEMBL1182312

SMILES NCCc1ccc(Oc2ccc(O)cc2)c(I)c1

InChI Key InChIKey=XIINYOJWNGOUPF-UHFFFAOYSA-N

Data  6 EC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50359505   

TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50359505(CHEMBL1182312)
Affinity DataEC50:  189nMAssay Description:Agonist activity at mouse TAAR1 expressed in HEK293 cells coexpressing cAMP BRET biosensor assessed as induction of CAMP production after 20 mins by ...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359505(CHEMBL1182312)
Affinity DataEC50:  22.4nMAssay Description:Activation of rat TAAR1 expressed in Syrian hamster AV12-664 cells assessed as accumulation of cAMP after 30 mins using cAMP XS EA/CL as substrate by...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359505(CHEMBL1182312)
Affinity DataEC50:  225nMAssay Description:Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359505(CHEMBL1182312)
Affinity DataEC50:  1.69E+3nMAssay Description:Inhibition of full length recombinant human N-terminal HA-tagged/C-terminal FLAG-tagged TAAR1 expressed in CHOK1 cells assessed as increase in cAMP a...More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50359505(CHEMBL1182312)
Affinity DataEC50:  189nMAssay Description:Agonist activity at mouse TAAR1More data for this Ligand-Target Pair
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359505(CHEMBL1182312)
Affinity DataEC50:  1.51E+3nMAssay Description:Activation of human TAAR1 expressed in Syrian hamster AV12-664 cells co-expressing GalphaS protein assessed as accumulation of cAMP after 30 mins usi...More data for this Ligand-Target Pair