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BDBM50359666 CHEMBL1929032

SMILES: Fc1ccccc1-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F

InChI Key: InChIKey=UVYDCAROMGQSPH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359666   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM50359666
PNG
(CHEMBL1929032)
Show SMILES Fc1ccccc1-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F
Show InChI InChI=1S/C18H11F4N3O2/c19-11-3-1-2-4-13(11)25-14(8-16(24-25)18(20,21)22)10-5-6-15-12(7-10)23-17(26)9-27-15/h1-8H,9H2,(H,23,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 440n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting


J Med Chem 54: 8616-31 (2011)


Article DOI: 10.1021/jm2011645
BindingDB Entry DOI: 10.7270/Q21G0MP5
More data for this
Ligand-Target Pair