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BDBM50359987 CHEMBL1927778

SMILES: FC(F)(F)c1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(Br)ccc32)cc(c1)C(F)(F)F

InChI Key: InChIKey=LXAIOMVXAKICRS-CYLJNIGPNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359987   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50359987
PNG
(CHEMBL1927778)
Show SMILES FC(F)(F)c1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(Br)ccc32)cc(c1)C(F)(F)F
Show InChI InChI=1/C34H23BrF6N4O2S/c35-24-8-11-28-29(17-24)48-32-44-27(18-45(28)32)21-6-9-25(10-7-21)42-31(47)26(14-19-4-2-1-3-5-19)43-30(46)15-20-12-22(33(36,37)38)16-23(13-20)34(39,40)41/h1-13,16-18,26H,14-15H2,(H,42,47)(H,43,46)/t26-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.30E+3n/an/an/an/an/an/a



University of the Mediterranean

Curated by ChEMBL


Assay Description
Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...


Eur J Med Chem 47: 239-54 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.051
BindingDB Entry DOI: 10.7270/Q2XK8FZT
More data for this
Ligand-Target Pair