BDBM50360303 CHEMBL1933290::US9150577, 99

SMILES CN(C)CCCn1c(NC(=O)c2ccc3cc4C(=O)NCC(C)(C)Cn4c3c2)nc2ccccc12

InChI Key InChIKey=LQZKYXLZCLMOGP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360303   

TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50360303(CHEMBL1933290 | US9150577, 99)
Affinity DataIC50:  27nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50360303(CHEMBL1933290 | US9150577, 99)
Affinity DataIC50:  290nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50360303(CHEMBL1933290 | US9150577, 99)
Affinity DataIC50:  27nMAssay Description:Inhibition of human RSK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed