BDBM50360305 CHEMBL409855::US9149492, Beauveriolide III
SMILES CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@H]([C@@H](C)CC)C(=O)O1
InChI Key InChIKey=VEELKRGSLCNVAR-QVZGIDAOSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50360305
Affinity DataIC50: 900nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of ACAT1- mediated cholesteryl ester synthesis in macrophagesMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Tohoku Medical And Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair