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BDBM50360850 CHEMBL1933085

SMILES: CC(=O)Nc1cccc(c1)C1CCN(CCCn2nc(-c3ccc(cc3)C(F)(F)F)c3ccccc3c2=O)CC1

InChI Key: InChIKey=LWZOLPCYBYTCPD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360850   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50360850
PNG
(CHEMBL1933085)
Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCn2nc(-c3ccc(cc3)C(F)(F)F)c3ccccc3c2=O)CC1
Show InChI InChI=1S/C31H31F3N4O2/c1-21(39)35-26-7-4-6-24(20-26)22-14-18-37(19-15-22)16-5-17-38-30(40)28-9-3-2-8-27(28)29(36-38)23-10-12-25(13-11-23)31(32,33)34/h2-4,6-13,20,22H,5,14-19H2,1H3,(H,35,39)
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Similars

Article
PubMed
n/an/a 136n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of Eu-MCH from human recombinant MCH-R1 expressed in CHO cell membrane after 90 mins by time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 427-30 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.111
BindingDB Entry DOI: 10.7270/Q2F76D09
More data for this
Ligand-Target Pair