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BDBM50360900 CHEMBL1935112

SMILES: CC1CC(=O)NN=C1c1ccc(OCCCN2CCCC2)cc1

InChI Key: InChIKey=SMIRNBCIQIPOFS-UHFFFAOYNA-N

Data: 2 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50360900   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50360900
PNG
(CHEMBL1935112)
Show SMILES CC1CC(=O)NN=C1c1ccc(OCCCN2CCCC2)cc1
Show InChI InChI=1/C18H25N3O2/c1-14-13-17(22)19-20-18(14)15-5-7-16(8-6-15)23-12-4-11-21-9-2-3-10-21/h5-8,14H,2-4,9-13H2,1H3,(H,19,22)
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PC sid
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Article
PubMed
83n/an/an/an/an/an/an/an/a



Cephalon Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 22: 194-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.037
BindingDB Entry DOI: 10.7270/Q25Q4WJV
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50360900
PNG
(CHEMBL1935112)
Show SMILES CC1CC(=O)NN=C1c1ccc(OCCCN2CCCC2)cc1
Show InChI InChI=1/C18H25N3O2/c1-14-13-17(22)19-20-18(14)15-5-7-16(8-6-15)23-12-4-11-21-9-2-3-10-21/h5-8,14H,2-4,9-13H2,1H3,(H,19,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
85n/an/an/an/an/an/an/an/a



Cephalon Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 22: 194-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.037
BindingDB Entry DOI: 10.7270/Q25Q4WJV
More data for this
Ligand-Target Pair