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BDBM50360958 CHEMBL1935279

SMILES: CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(cc21)-n1cccn1)C(O)=O

InChI Key: InChIKey=VQQBCGJKDAMCHZ-IBGZPJMESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360958   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-12 (MMP12)


(Homo sapiens (Human))
BDBM50360958
PNG
(CHEMBL1935279)
Show SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(cc21)-n1cccn1)C(O)=O
Show InChI InChI=1S/C20H19N3O5S/c1-12(2)19(20(24)25)22-29(26,27)14-5-6-15-16-10-13(23-9-3-8-21-23)4-7-17(16)28-18(15)11-14/h3-12,19,22H,1-2H3,(H,24,25)/t19-/m0/s1
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human MMP-12


Bioorg Med Chem Lett 22: 138-43 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.046
BindingDB Entry DOI: 10.7270/Q2SJ1M20
More data for this
Ligand-Target Pair