BDBM50361053 CHEMBL1935601

SMILES Fc1cccc(c1)S(=O)(=O)c1ccc2c3CCNC4(CCCOC4)c3oc2c1

InChI Key InChIKey=OVDCCBDDPCBOAW-UHFFFAOYSA-N

Data  5 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50361053   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataKi:  16.9nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataKi:  16.9nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of human ERG by patch express assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of human ERG by patch express assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human ERG by patch express assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50:  9.80nMAssay Description:Antagonist activity at human recombinant 5-HT6 receptor expressed human astrocytoma cells assessed as inhibition of 5-HT-induced cAMP accumulation af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed