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BDBM50361443 CHEMBL1934409

SMILES: Nc1nc2n(CC(COCP(O)(O)=O)OCC(O)=O)cnc2c(=O)[nH]1

InChI Key: InChIKey=YRDQHYTYGMNROH-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361443   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)


(Homo sapiens (Human))
BDBM50361443
PNG
(CHEMBL1934409)
Show SMILES Nc1nc2n(CC(COCP(O)(O)=O)OCC(O)=O)cnc2c(=O)[nH]1
Show InChI InChI=1/C11H16N5O8P/c12-11-14-9-8(10(19)15-11)13-4-16(9)1-6(24-3-7(17)18)2-23-5-25(20,21)22/h4,6H,1-3,5H2,(H,17,18)(H2,20,21,22)(H3,12,14,15,19)
PDB
MMDB

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PC sid
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Similars

Article
PubMed
5.00E+3n/an/an/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of human HGPRT by spectrophotometric analysis in absence of PPi


Bioorg Med Chem 20: 1222-30 (2012)


Article DOI: 10.1016/j.bmc.2011.12.034
BindingDB Entry DOI: 10.7270/Q25M665C
More data for this
Ligand-Target Pair