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BDBM50361656 CHEMBL1940479

SMILES: COc1cccc2c(c[nH]c12)C(=O)CN1CCC(Cc2ccccc2)CC1

InChI Key: InChIKey=MYFZFVQBSXPENG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361656   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM50361656
PNG
(CHEMBL1940479)
Show SMILES COc1cccc2c(c[nH]c12)C(=O)CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H26N2O2/c1-27-22-9-5-8-19-20(15-24-23(19)22)21(26)16-25-12-10-18(11-13-25)14-17-6-3-2-4-7-17/h2-9,15,18,24H,10-14,16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.91E+3n/an/an/an/an/an/a



Universit£ di Messina

Curated by ChEMBL


Assay Description
Displacement of [3H]ifenprodil from GluN2B/NMDA in Wistar rat cerebral cortex after 120 mins by scintillation counting


J Med Chem 54: 8702-6 (2011)


Article DOI: 10.1021/jm2008002
BindingDB Entry DOI: 10.7270/Q2ZW1MBK
More data for this
Ligand-Target Pair