BDBM50361774 CHEMBL1938510

SMILES C[C@H]([C@H](NC(=O)C(C)(C)N)C(=O)NC(c1ccncc1)c1ccc(Cl)cc1)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=BDTZGVGKDZTCTN-XBJAUQGGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361774   

TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361774(CHEMBL1938510)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361774(CHEMBL1938510)
Affinity DataIC50:  6nMAssay Description:Inhibition of PrCP-mediated conversion of Ang3 to Ang(2-7) in mouse plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361774(CHEMBL1938510)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant mouse PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed