Found 4 hits for monomerid = 50362079 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50362079
(CHEMBL1940263)Show SMILES COc1cccc(c1)S(=O)(=O)NCc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C24H23N3O6S/c1-30-18-5-4-6-19(11-18)34(28,29)27-14-16-7-9-17(10-8-16)33-24-20-12-22(31-2)23(32-3)13-21(20)25-15-26-24/h4-13,15,27H,14H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR3 phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase receptor FLT3
(Homo sapiens (Human)) | BDBM50362079
(CHEMBL1940263)Show SMILES COc1cccc(c1)S(=O)(=O)NCc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C24H23N3O6S/c1-30-18-5-4-6-19(11-18)34(28,29)27-14-16-7-9-17(10-8-16)33-24-20-12-22(31-2)23(32-3)13-21(20)25-15-26-24/h4-13,15,27H,14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor (CSF1R)
(Homo sapiens (Human)) | BDBM50362079
(CHEMBL1940263)Show SMILES COc1cccc(c1)S(=O)(=O)NCc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C24H23N3O6S/c1-30-18-5-4-6-19(11-18)34(28,29)27-14-16-7-9-17(10-8-16)33-24-20-12-22(31-2)23(32-3)13-21(20)25-15-26-24/h4-13,15,27H,14H2,1-3H3 | UniProtKB/SwissProt
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50362079
(CHEMBL1940263)Show SMILES COc1cccc(c1)S(=O)(=O)NCc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1 Show InChI InChI=1S/C24H23N3O6S/c1-30-18-5-4-6-19(11-18)34(28,29)27-14-16-7-9-17(10-8-16)33-24-20-12-22(31-2)23(32-3)13-21(20)25-15-26-24/h4-13,15,27H,14H2,1-3H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
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