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BDBM50362512 CHEMBL1940980

SMILES: C[C@H]1COc2c(NCCCn3cccn3)c(F)c(N)c3c2n1cc(C(O)=O)c3=O

InChI Key: InChIKey=ORAKRBLBWOVZSD-JTQLQIEISA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362512   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Axin-1/Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50362512
PNG
(CHEMBL1940980)
Show SMILES C[C@H]1COc2c(NCCCn3cccn3)c(F)c(N)c3c2n1cc(C(O)=O)c3=O
Show InChI InChI=1S/C19H20FN5O4/c1-10-9-29-18-15(22-4-2-6-24-7-3-5-23-24)13(20)14(21)12-16(18)25(10)8-11(17(12)26)19(27)28/h3,5,7-8,10,22H,2,4,6,9,21H2,1H3,(H,27,28)/t10-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



ActivX Biosciences Inc

Curated by ChEMBL


Assay Description
Inhibition of GSK3-beta


Bioorg Med Chem Lett 22: 1005-8 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.006
BindingDB Entry DOI: 10.7270/Q2930TMF
More data for this
Ligand-Target Pair