BDBM50364429 CHEMBL1950570

SMILES N[C@H](CC(=O)Nc1ccc(-c2nc3ccc(nc3s2)C2(CC2)c2ccccc2)c(F)c1)C(O)=O

InChI Key InChIKey=HVYSRLPOSBCBIE-GOSISDBHSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364429   

TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364429(CHEMBL1950570)
Affinity DataEC50: >2.50E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing chimeric Gq/i5 G-protein assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364429(CHEMBL1950570)
Affinity DataEC50:  2nMAssay Description:Agonist activity at eGFP-tagged human S1P1 receptor expressed in U2OS cells assessed as receptor internalization after 1 hr by Hoechst dye-based micr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed