BDBM50365617 CHEMBL1958142

SMILES Cc1ccc2nc(c(NC3CCCCC3)n2c1)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=XITSTCZDUMMNGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365617   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50365617(CHEMBL1958142)
Affinity DataIC50: 80nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50365617(CHEMBL1958142)
Affinity DataIC50: 260nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed