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BDBM50365943 CHEMBL1956215

SMILES: COc1cc2nncc(-c3ccc(C)nc3)c2cc1OC

InChI Key: InChIKey=UONJPSDTLULUQK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365943   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50365943
PNG
(CHEMBL1956215)
Show SMILES COc1cc2nncc(-c3ccc(C)nc3)c2cc1OC
Show InChI InChI=1S/C16H15N3O2/c1-10-4-5-11(8-17-10)13-9-18-19-14-7-16(21-3)15(20-2)6-12(13)14/h4-9H,1-3H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a 181n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Inhibition of PDE10A


Bioorg Med Chem Lett 22: 2262-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.086
BindingDB Entry DOI: 10.7270/Q2ZK5H42
More data for this
Ligand-Target Pair