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BDBM50366187 CHEMBL1957586

SMILES: NC(=O)[C@@H]1CCC(=O)N1Cc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=YQCQHFRCABEIDV-XISACWJONA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50366187   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50366187
PNG
(CHEMBL1957586)
Show SMILES NC(=O)[C@@H]1CCC(=O)N1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1/C18H18N2O2/c19-18(22)16-10-11-17(21)20(16)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,16H,10-12H2,(H2,19,22)/t16-/s2
PDB
MMDB

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Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Colosseum Combinatorial Chemistry Centre for Technology (C4T SCarl)

Curated by ChEMBL


Assay Description
Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...


Bioorg Med Chem 20: 2323-37 (2012)


Article DOI: 10.1016/j.bmc.2012.02.010
BindingDB Entry DOI: 10.7270/Q2N29XD5
More data for this
Ligand-Target Pair