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NORCANTHARIDIN CHEBI:799563::Norcantharidin

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match
png missing

Other Databases links: PubChem cid PubChem sid

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50366474    Zinc 0: unavailable per Zinc DB. Zinc 1: purchasable, 2 weeks to supply. Zinc 2: made on demand. Zinc 4: potentially available
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein phosphatase 2C beta


(Homo sapiens)
NORCANTHARIDIN
PNG
(CHEBI:799563 | Norcantharidin)
Show SMILES O=C1OC(=O)[C@@H]2[C@H]3CC[C@@H](O3)[C@H]12 |r,TLB:1:11:8.7:10,THB:3:5:8.7:10|
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid

Similars

AffyNet 
Article
PubMed
n/an/a 1980.0n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant Protein phosphatase 1


Citation and Details

More data for this
Ligand-Target Pair
Serine-threonine protein phosphatase 2A regulatory subunit


(Gallus gallus)
NORCANTHARIDIN
PNG
(CHEBI:799563 | Norcantharidin)
Show SMILES O=C1OC(=O)[C@@H]2[C@H]3CC[C@@H](O3)[C@H]12 |r,TLB:1:11:8.7:10,THB:3:5:8.7:10|
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid

Similars

AffyNet 
Article
PubMed
n/an/a 2100.0n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Concentration required to inhibit the action of protein phosphatase 2A


Citation and Details

More data for this
Ligand-Target Pair
Protein phosphatase 2C beta


(Homo sapiens)
NORCANTHARIDIN
PNG
(CHEBI:799563 | Norcantharidin)
Show SMILES O=C1OC(=O)[C@@H]2[C@H]3CC[C@@H](O3)[C@H]12 |r,TLB:1:11:8.7:10,THB:3:5:8.7:10|
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid

Similars

AffyNet 
Article
PubMed
n/an/a 5310.0n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 1 (PP1) was determined


Citation and Details

More data for this
Ligand-Target Pair
Protein phosphatase 2C beta


(Homo sapiens)
NORCANTHARIDIN
PNG
(CHEBI:799563 | Norcantharidin)
Show SMILES O=C1OC(=O)[C@@H]2[C@H]3CC[C@@H](O3)[C@H]12 |r,TLB:1:11:8.7:10,THB:3:5:8.7:10|
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid

Similars

AffyNet 
Article
PubMed
n/an/a 570.0n/an/an/an/an/an/a



University of California at Irvine

Curated by ChEMBL


Assay Description
Inhibitory activity against protein phosphatase-1 from rabbit skeletal muscle


Citation and Details

More data for this
Ligand-Target Pair
Serine-threonine protein phosphatase 2A regulatory subunit


(Gallus gallus)
NORCANTHARIDIN
PNG
(CHEBI:799563 | Norcantharidin)
Show SMILES O=C1OC(=O)[C@@H]2[C@H]3CC[C@@H](O3)[C@H]12 |r,TLB:1:11:8.7:10,THB:3:5:8.7:10|
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid

Similars

AffyNet 
Article
PubMed
n/an/a 370.0n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibitory activity against partially purified (chicken skeletal muscle) Protein phosphatase 2A


Citation and Details

More data for this
Ligand-Target Pair
Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform


(Mus musculus)
NORCANTHARIDIN
PNG
(CHEBI:799563 | Norcantharidin)
Show SMILES O=C1OC(=O)[C@@H]2[C@H]3CC[C@@H](O3)[C@H]12 |r,TLB:1:11:8.7:10,THB:3:5:8.7:10|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid

Similars

AffyNet 
n/an/a 70000.0n/an/an/an/an/an/a


TBA

Assay Description
Compound was tested for inhibitory concentration of Protein Phosphatase 2A (PP2A).


Citation and Details

More data for this
Ligand-Target Pair
Serine-threonine protein phosphatase 2A regulatory subunit


(Gallus gallus)
NORCANTHARIDIN
PNG
(CHEBI:799563 | Norcantharidin)
Show SMILES O=C1OC(=O)[C@@H]2[C@H]3CC[C@@H](O3)[C@H]12 |r,TLB:1:11:8.7:10,THB:3:5:8.7:10|
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid

Similars

AffyNet 
Article
PubMed
n/an/a 2900.0n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein phosphatase 2A (PP2A) was determined


Citation and Details

More data for this
Ligand-Target Pair