BDBM50072147 (2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)succinonitrile::1,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene::1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene monoethanolate::2,3-Bis-[1-amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-ylidene]-succinonitrile::2,3-Bis-[amino-(2-amino-phenylsulfanyl)-methylene]-succinonitrile::2,3-bis(amino(2-aminophenylthio)methylene)succinonitrile::2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-ylidene]-3-[1-amino-1-(2-amino-phenylsulfanyl)-meth-(E)-ylidene]-succinonitrile::2-[Amino-(2-amino-phenylsulfanyl)-methylene]-3-[1-amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-ylidene]-succinonitrile::CHEMBL100473::CHEMBL95758::U-0126

SMILES: Nc1ccccc1SC(=N)C(C#N)C(C#N)C(=N)Sc1ccccc1N

InChI Key: InChIKey=ZCHZSBUNJOCWCW-UHFFFAOYSA-N

Data: 27 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50072147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
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Malate dehydrogenase (Thermus thermophilus)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 5 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsinogen B (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity mitogen-activated protein kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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MAP kinase-activated protein kinase 5 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50072147 (CHEMBL100473 | 2,3-Bis-[1-amino-1-(2-amino-phenyls...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair