BDBM50366826 DR-3355::Floxacin::Iquix::LEVOFLOXACIN::Levaquin

SMILES: C[C@H]1COc2c3c(cc(c2N4CCN(CC4)C)F)C(=O)C(=CN31)C(=O)O

InChI Key: InChIKey=GSDSWSVVBLHKDQ-UHFFFAOYSA-N

Data: 2 KI  35 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50366826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Multidrug and toxin extrusion protein 1 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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DNA primase (Bacillus anthracis)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	8.8	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus-Staphylococcus aureus (strai...)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Rat)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.80E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.66E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-beta (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Staphylococcus aureus)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.41E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.13E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-beta (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-beta (Human)	BDBM50366826 (Levaquin | Iquix | Floxacin | DR-3355 | LEVOFLOXAC...) Show SMILES Show InChI	GoogleScholar	UniChem		9.96E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair