BDBM50367055 4-Aminofolic acid::4-Aminopteroic acid::AMINOPTERIN::Aminopteroylglutamic acid

SMILES: c1cc(ccc1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCc2cnc3c(n2)c(nc(n3)N)N

InChI Key: InChIKey=TVZGACDUOSZQKY-UHFFFAOYSA-N

Data: 8 KI  11 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50367055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1A3 (Rat)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Folylpolyglutamate synthase, mitochondrial (Mouse)	BDBM50367055 (4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...) Show SMILES Show InChI	GoogleScholar	UniChem		1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair