BDBM50368347 CHEMBL610655

SMILES CCCCCC#Cc1nc(N)c2ncn(C3O[C@@H]([C@@H](O)[C@H]3O)C(=O)NCC)c2n1

InChI Key InChIKey=CXZRALAESZDRAF-UHFFFAOYSA-N

Data  5 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50368347   

TargetAdenosine receptor A2a/A2b(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataKi:  4.70nMAssay Description:Binding affinity against A2 adenosine receptors from rat striatal membranes with 50 nM CPA using [3H]NECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataKi:  37nMAssay Description:Maximal NECA stimulation of adenylate cyclase via Adenosine A2 receptor in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataKi:  89nMAssay Description:Binding affinity against Adenosine A1 receptor from rat brain membranes using [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataKi:  171nMAssay Description:Binding affinity against high affinity component of Adenosine A1 receptor from rat brain membranes using [3H]-DPCPXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataEC50:  388nMAssay Description:Maximal NECA stimulation of adenylate cyclase via A2 receptors in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataKi:  2.91E+3nMAssay Description:Binding affinity against low affinity component of Adenosine A1 receptor from rat brain membranes using [3H]DPCPXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50368347(CHEMBL610655)
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of adenylate cyclase via Adenosine A1 receptor in rat fat cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed