BDBM50368452 CHEMBL4168305

SMILES: CC(C)c1ccc(cc1C#Cc2cnc3n2ccnc3)C(=O)Nc4cc(cc(c4)C(F)(F)F)CN5CCN(CC5)C

InChI Key: InChIKey=IUGBGEUCXVKGQK-UHFFFAOYSA-N

Data: 5 IC50  12 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50368452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-A receptor 7 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 10 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-B receptor 2 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-A receptor 8 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	494	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Human)	BDBM50368452 (CHEMBL4168305) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair